ZO® Skin Health, founded by Dr. Zein Obagi, is grounded in the latest scientific advances and cutting-edge dermatological research. The brand’s formulations incorporate powerful ingredients, patented technologies, and innovative delivery systems that go beyond traditional skincare to target skin health at a deeper level. ZO products are specifically designed to strengthen the skin’s natural barrier, improve cellular function, and promote long-term skin vitality. With a focus on optimizing skin health rather than merely treating symptoms, ZO offers targeted solutions for various skin concerns, including hyperpigmentation, acne, rosacea, and aging, all backed by rigorous clinical research and continuous innovation.

It is essential to purchase ZO® Medical products exclusively from authorised clinics to ensure product authenticity and safety. ZO Skin Health products are never sold online, and buying from unauthorised retailers, including platforms like Amazon, poses significant risks such as exposure to counterfeit, expired, or tampered products that can potentially damage your skin. For guaranteed safety, effectiveness, and optimal results, always purchase ZO products from official clinic stockists authorised by the brand.

Defense Against Oxidative Damage: The serum contains potent antioxidants, such as Vitamins A and E, which help neutralize free radicals and protect the skin from oxidative stress caused by environmental factors.

Reduction of Premature Aging Signs: By promoting collagen production and cellular activity, Daily Power Defense helps diminish the appearance of fine lines and wrinkles, leading to a more youthful complexion.

Barrier Restoration and Hydration: The inclusion of ZPOLY™, an exclusive plant-derived polysaccharide complex, accelerates the restoration of the skin's barrier function and provides extended hydration, ensuring the skin remains supple and resilient.

Support for Overall Skin Health: The serum's formulation supports continuous skin health by enhancing the skin's natural repair processes and maintaining its structural integrity.

All Skin Types

Use as directed by your practitioner in your “Skin Health Treatment Plan”.

For general guidance:

Begin by cleansing your face to remove impurities and prepare your skin for treatment.

Apply 2–3 pumps of Daily Power Defense to your face and neck. Gently massage the serum into your skin using upward, circular motions to promote absorption.

Use the serum twice daily, in the morning (AM) and evening (PM), to maintain continuous protection and support for your skin.

After applying Daily Power Defense, proceed with your regular skincare regimen

Ultrasomes (UV-endonuclease) and roxisomes (glycosylase):  Introduces enzymes to help speed up the skin’s natural repair process

Vitamin E: Provides antioxidant properties.

Ceramide 6: Helps restore barrier function.

Matrixyl 3000 (palmitoyl oligopeptide and palmitoyl tetrapeptide-7): Firms and re-densifies.

Aqua/Water/Eau, Cetearyl Isononanoate, Cyclopentasiloxane, Glycerin, Cyclohexasiloxane, Pentylene Glycol, Cetearyl Alcohol, Steareth-20, Jojoba Esters, C14-22 Alcohols, Cetearyl Glucoside, Safflower Oil/Palm Oil Aminopropanediol Esters, C12-20 Alkyl Glucoside, Carbomer, Lactose, Cellulose, Lecithin, Retinol, Beta-Glucan, 1,2-Hexanediol, Hydroxypropyl Methylcellulose, Micrococcus Lysate, Arabidopsis Thaliana Extract, Citrus Aurantium Dulcis (Orange) Peel Oil, Citrus Nobilis (Mandarin Orange) Peel Oil, Citrus Reticulata (Tangerine) Peel Oil, Citrus Limon (Lemon) Peel Oil, Mentha Piperita (Peppermint) Oil, Mimosa Tenuiflora Bark Extract, Citrus Reticulata (Tangerine) Fruit Extract, Polysorbate 20, Farnesol, Limonene, Disodium EDTA, Sodium Hydroxide, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Retinyl Palmitate, Tocopheryl Acetate, Caprylyl Glycol, Butylene Glycol, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol, Ultramarines (CI 77007), Ext. Violet 2 (CI 60730).